Our Lab

Pacific Hills Farms owns and operates its own laboratory to test, distill, and package CBD in-house. With an integrated team, our lab work directly informs our farming and visa versa. This gives us the agility to test  throughout the growing season and to provide our customers with traceable sourcing in every product.

 

CBD + Wellness: A Note From the Lab
One of the most abundant chemical components from Cannabis sativa, or cannabis, plant is cannabidiol, otherwise known as CBD.  This chemical is part of a group of similarly structured compounds referred to as cannabinoids.  Another well-known cannabinoid is the psychoactive compound THC. Unlike THC, CBD does not produce a similar physiological response in humans.  Instead, anecdotal evidence points towards a different set of therapeutic responses to CBD. For example, people have reported positive outcomes from using CBD when experiencing pain from arthritis and muscle tension, as well as anxiety reduction. 

Furthermore, a growing body of non-clinical research has been performed in recent years suggesting pharmacological effects from CBD.  This research focuses mostly on in vitro and in vivo studies performed within the confines of academic laboratory settings, meaning their results have not been verified to have the same effects within humans.  From these studies, CBD has been found to exhibit neuroprotective, anti-inflammatory, and analgesic properties, among others.  These findings illustrate the therapeutic potential of CBD within the human body.  Another promising indication of CBD’s potential is the 2018 FDA approval for the prescription drug Epidiolex.  This drug uses a purified form of CBD to treat patients suffering from specific forms of epilepsy. Now that hemp cultivation has been legalized, we can expect more research will be completed that will further our understanding of the therapeutic benefits of CBD within the human body.

Another potential component to CBD’s promising health benefits centers around the “entourage effect”.  This term describes the synergic effect when CBD is combined with other compounds from cannabis, mainly terpenes and other non-THC cannabinoids.  Terpenes impart the aromatic character to many plants, with cannabis sharing several terpenes also found in hops, citrus fruits, pine trees, and cinnamon.  Terpenes predominantly found in cannabis include limonene, beta-myrcene, beta-caryophyllene, alpha-pinene, and linalool. Non-clinical experimental evidence has shown that these terpenes exhibit similar effects to CBD, such as anti-inflammatory, analgesic, and anxiolytic effects.  Some terpenes also have demonstrated antibacterial properties. The theory behind the entourage effect is that a particular combination of cannabinoids and terpenes elicit an increased effect over pure CBD by interacting with the human body through separate mechanisms (1) to increase the effectiveness of CBD or (2) to elicit a similar biological response.

REFERENCES:

  1. Andre CM, Hausman JF, Guerriero G. Cannabis sativa: The Plant of the Thousand and One Molecules. Front Plant Sci. 2016;7:19. Published 2016 Feb 4.
  2. Bow EW, Rimoldi JM. The Structure-Function Relationships of Classical Cannabinoids: CB1/CB2 Modulation. Perspect Medicin Chem. 2016;8:17–39. Published 2016 Jun 28. 
  3. Hartsel, Joshua & Eades, Joshua & Hickory, Brian & Makriyannis, Alexandros. (2016). Chapter Title: Cannabis sativa and Hemp.
  4. Manzanares J, Julian M, Carrascosa A. Role of the cannabinoid system in pain control and therapeutic implications for the management of acute and chronic pain episodes. Curr Neuropharmacol. 2006;4(3):239–257. 
  5. Pisanti, S., et al., Cannabidiol: State of the art and new challenges for therapeutic applications. Pharmacol Ther. 2017;175:133-150.
  6. Russo EB. Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects. Br J Pharmacol. 2011;163(7):1344–1364.

Natural Products

Products are developed with natural ingredients and sustainably grown hemp

Natural Products
Natural Products

South Farm

Harvest Photos, 2019

South Farm
South Farm